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Concept
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Arthritis, Experimental
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Academic Article
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Cartilage proteoglycan-induced arthritis in BALB/c mice. Antibodies that recognize human and mouse cartilage proteoglycan and can cause depletion of cartilage proteoglycan with little or no synovitis.
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Academic Article
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Proteoglycan-specific autoreactive antibodies and T-lymphocytes in experimental arthritis and human rheumatoid joint diseases.
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Academic Article
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Proteoglycan-induced arthritis in BALB/c mice. Clinical features and histopathology.
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Academic Article
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VDIPEN, a metalloproteinase-generated neoepitope, is induced and immunolocalized in articular cartilage during inflammatory arthritis.
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Academic Article
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Proteoglycan (aggrecan)-induced arthritis in BALB/c mice is a Th1-type disease regulated by Th2 cytokines.
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Academic Article
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Complex pattern of Th1 and Th2 activation with a preferential increase of autoreactive Th1 cells in BALB/c mice with proteoglycan (aggrecan)-induced arthritis.
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Academic Article
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Th1 and Th2 cytokines regulate proteoglycan-specific autoantibody isotypes and arthritis.
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Academic Article
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Continuous nasal administration of antigen is critical to maintain tolerance in adoptively transferred autoimmune arthritis in SCID mice.
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Academic Article
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Cartilage-specific constitutive expression of TSG-6 protein (product of tumor necrosis factor alpha-stimulated gene 6) provides a chondroprotective, but not antiinflammatory, effect in antigen-induced arthritis.
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Academic Article
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Combined autoimmune models of arthritis reveal shared and independent qualitative (binary) and quantitative trait loci.
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Academic Article
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Collagen-induced arthritis is exacerbated in IL-10-deficient mice.
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Academic Article
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Sex effect on clinical and immunologic quantitative trait loci in a murine model of rheumatoid arthritis.
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Academic Article
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Differential recognition of altered peptide ligands distinguishes two functionally discordant (arthritogenic and nonarthritogenic) autoreactive T cell hybridoma clones.
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Academic Article
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Disease-associated qualitative and quantitative trait loci in proteoglycan-induced arthritis and collagen-induced arthritis.
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Academic Article
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Achievement of a synergistic adjuvant effect on arthritis induction by activation of innate immunity and forcing the immune response toward the Th1 phenotype.
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Academic Article
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Proteoglycan aggrecan-induced arthritis: a murine autoimmune model of rheumatoid arthritis.
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Academic Article
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A longitudinal study on an autoimmune murine model of ankylosing spondylitis.
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Academic Article
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Gene expression profiling in murine autoimmune arthritis during the initiation and progression of joint inflammation.
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Academic Article
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Antigen-specific B cells are required as APCs and autoantibody-producing cells for induction of severe autoimmune arthritis.
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Academic Article
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Molecular manipulation with the arthritogenic epitopes of the G1 domain of human cartilage proteoglycan aggrecan.
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Academic Article
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Naive transgenic T cells expressing cartilage proteoglycan-specific TCR induce arthritis upon in vivo activation.
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Academic Article
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Increased arthritis susceptibility in cartilage proteoglycan-specific T cell receptor-transgenic mice.
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Academic Article
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Antigen-induced differential gene expression in lymphocytes and gene expression profile in synovium prior to the onset of arthritis.
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Academic Article
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Inhibition of indoleamine 2,3-dioxygenase-mediated tryptophan catabolism accelerates collagen-induced arthritis in mice.
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Academic Article
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IL-27 induces a Th1 immune response and susceptibility to experimental arthritis.
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Academic Article
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Two loci on chromosome 15 control experimentally induced arthritis through the differential regulation of IL-6 and lymphocyte proliferation.
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Academic Article
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Congenic strains displaying similar clinical phenotype of arthritis represent different immunologic models of inflammation.
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Academic Article
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IL-10 is critically involved in mycobacterial HSP70 induced suppression of proteoglycan-induced arthritis.
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Academic Article
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BALB/c mice genetically susceptible to proteoglycan-induced arthritis and spondylitis show colony-dependent differences in disease penetrance.
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Academic Article
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Th1/Th17 polarization and acquisition of an arthritogenic phenotype in arthritis-susceptible BALB/c, but not in MHC-matched, arthritis-resistant DBA/2 mice.
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Academic Article
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The genetic background of ankylosing spondylitis.
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Academic Article
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IFN-gamma regulates the requirement for IL-17 in proteoglycan-induced arthritis.
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Academic Article
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Development of proteoglycan-induced arthritis depends on T cell-supported autoantibody production, but does not involve significant influx of T cells into the joints.
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Academic Article
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Impaired activation-induced cell death promotes spontaneous arthritis in antigen (cartilage proteoglycan)-specific T cell receptor-transgenic mice.
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Academic Article
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Proteoglycan-induced arthritis and recombinant human proteoglycan aggrecan G1 domain-induced arthritis in BALB/c mice resembling two subtypes of rheumatoid arthritis.
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Academic Article
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B cell depletion enhances T regulatory cell activity essential in the suppression of arthritis.
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Academic Article
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T cell receptor (TCR) signal strength controls arthritis severity in proteoglycan-specific TCR transgenic mice.
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Academic Article
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Disease-promoting and -protective genomic loci on mouse chromosomes 3 and 19 control the incidence and severity of autoimmune arthritis.
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Academic Article
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Suppression of dendritic cell maturation and T cell proliferation by synovial fluid myeloid cells from mice with autoimmune arthritis.
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Academic Article
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Arthritogenic T cells drive the recovery of autoantibody-producing B cell homeostasis and the adoptive transfer of arthritis in SCID mice.
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Academic Article
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In vivo two-photon imaging of T cell motility in joint-draining lymph nodes in a mouse model of rheumatoid arthritis.
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Academic Article
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The role of citrullination of an immunodominant proteoglycan (PG) aggrecan T cell epitope in BALB/c mice with PG-induced arthritis.
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Academic Article
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Location of CD4+ T cell priming regulates the differentiation of Th1 and Th17 cells and their contribution to arthritis.
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Academic Article
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Differentially expressed epigenome modifiers, including aurora kinases A and B, in immune cells in rheumatoid arthritis in humans and mouse models.
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Academic Article
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Brief report: Autologous stem cell transplantation restores immune tolerance in experimental arthritis by renewal and modulation of the Teff cell compartment.
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Academic Article
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Proteoglycan aggrecan conducting T cell activation and apoptosis in a murine model of rheumatoid arthritis.
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Academic Article
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An Arthritis-Suppressive and Treg Cell-Inducing CD4+ T Cell Epitope Is Functional in the Context of HLA-Restricted T Cell Responses.
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Academic Article
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Immune Recognition of Citrullinated Proteoglycan Aggrecan Epitopes in Mice with Proteoglycan-Induced Arthritis and in Patients with Rheumatoid Arthritis.
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Academic Article
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Amelioration of Autoimmune Arthritis in Mice Treated With the DNA Methyltransferase Inhibitor 5'-Azacytidine.
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